Business
Achronix Semiconductor designs and manufactures two principal product lines: The Achronix-ULTRA line of ultra fast FPGAs, operating at near 2GHz, and the Achronix-XTREME line of fast FPGAs, designed to operate near 1GHz in high radiation and extreme temperature environments.

Technology
Achronix builds some of the world's fastest field programmable gate arrays (FPGAs) which use a unique, patented circuit technology from Cornell. The products, with a 2GHz throughput, provide a significant performance advantage over existing FPGA technology.

Cornell Connection
Licensed founding technology developed by Rajit Manohar of Electrical and Computer Engineering.

Business
Founded in 2005 as a "spin-out" from Cornell University's Ruminant Nutrition Modeling group, Agricultural Modeling and Training Systems, LLC (AMTS), combines 44 years of agricultural software development experience to offer high quality software tools to support the dairy and livestock markets. AMTS goes beyond offering a simple software suite and includes service offerings ranging from quality control to data mining while promoting environmental substainability.

Business
Animal Ultrasound Services, Inc. was acquired by Micro Beef Technologies in 2000. Animal Ultrasound Service’s product, AUSKey® image analysis software, evaluates ultrasonic images of live animals and carcasses.

Technology
AUSKey® is based on image analysis software that was developed at Cornell University.

Cornell Connection
The founding licensed software was created by James Stouffer of the College of Agriculture and Life Sciences.

Business
ArcScan makes Artemis, a very high frequency (VHF) ultrasound eye scanner. Following an eye scan, signal analysis is performed on a PC-compatible microcomputer, and the data are available for immediate viewing on an LCD monitor. ArcScan merged with Ultralink LLC September 2007 and is operating under the name of ArcScan.

Technology
Artemis is enabled by a suite of licensed Cornell technologies that address corneal measurement, scanning and imaging.

Cornell Connection
The founding licensed technologies were invented by Donald Jackson Coleman and Ronald Silverman of Weill Cornell Medical College.

Business
Avera, a neuropharmaceutical licensing and development Company, is developing a pipeline of drug candidates to treat irritable bowel syndrome, overactive bladder, cognitive impairment associated with schizophrenia, and dementia, as well as a neuromuscular blocking agent for both rapid and routine endotracheal intubation and skeletal muscle relaxation during surgery. The first drug candidate, AV965 is in Phase I trials, the second, AV608 is in Phase II, and the third, Gantacurium, is in Phase III.

Technology
The Cornell invention is entitled "Ultra-Short Acting Neuromuscular Blockers."

Cornell Connection
The founding drug compound was developed by John Savarese of the Weill Cornell Medical Center.

Business
BinOptics develops and manufactures photonic chips for optical transceivers and other applications in the telecom, datacom, and optical storage markets. The company's monolithically integrated laser chips are manufactured using its proprietary etched-facet technology. BinOptics is privately held and funded by Silicon Valley venture firm Draper Fisher Jurvetson, the Cayuga Venture Fund, FA Technology Ventures, ArrowPath Venture Partners, and STIC International.

Technology
BinOptic's proprietary technology is originally derived from four Cornell inventions that cover methods for optimizing direction control and optical logic for semiconductor lasers made with etched facets. The company has further developed and protected this approach with numerous patents and uses it for the large-scale manufacturing of lasers in a variety of material systems. The etched facet process allows cost effective wafer-scale processing and testing, as well as novel device designs that cannot be made by cleaving.

Cornell Connection
The founding inventions involving semiconductors were made by Alex Behfar, founder and current CEO of BinOptics, in collaboration with former professors Joseph Ballantyne and Simon Wong, College of Engineering. Mr. Behfar is a Cornell graduate with a PhD in EE.

Business
BioWorks sells RootShield, a biological fungicide for horticulture crops. RootShield protects roots from diseases caused by Pythium, Rhizoctonia and Fusarium. RootShield contains a hybrid strain of fungus called Trichoderma harzianum strain T-22 to prevent root diseases. BioWorks markets several other products based on environmentally responsible and safe alternatives, including MilStop® (potassium bicarbonate), NemaShield® (Steinernema feltiae), BotaniGard® (Beauveria bassiana), and Cease ™ (Bacillus subtilis).

Technology
T-22 is a special hybrid strain of fungus developed at Cornell University’s microbial breeding program.

Cornell Connection
Bioworks' founding inventions were created by Gary E. Harman’s lab, College of Agriculture and Life Sciences.

Business
CEA Systems develops advanced control systems to optimize controlled environment agriculture (CEA). The company's goal is to create a software-configurable, energy efficient module that is suitable for achieving exceptional production rates for conventional crops and genetically modified plants for pharmaceutical and/or nutraceutical production.

Technology
CEA Systems' agricultural methods and software are based on research conducted at Cornell University.

Cornell Connection
The algorithm that is the underpinning of this patented technology was invented by Louis Albright, College of Agriculture and Life Sciences.

Business
CoAxia&trade is a medical device company that is developing a new treatment for patients having an acute stroke. The concept involves increasing blood flow to the brain to minimize the damage of the stroke. CoAxia’s current business focus is demonstrating the safety and efficacy of its NeuroFlo™ catheter in FDA approved clinical studies and ultimately making it a widely available treatment option for stroke patients.

Technology
CoAxia's NeuroFlo™ catheter is dual balloon catheter inserted in the patient’s abdominal aorta which diverts blood flow from the lower part of the body to the brain.

Cornell Connection
The founding technology for CoAxia™’s NeuroFlo catheter was invented by Denise Barbut formerly at Weill Cornell Medical College.

Business

Databeast makes software that provides terminal emulation on the Macintosh for Internet or direct modem dialup connections.

Business
DNANO stands for DNA and NANO – "We Bring DNA and Nanotechnology Together". DNANO is commercializing 'P-Gel', a new protein-production platform that uses hydrogel to efficiently and economically produce proteins. P-Gel can cut product costs by an estimated twenty times over conventional protein-producing techniques. P-Gel produces a wide range of high-yield, low-cost, proteins, sidestepping the need for cells for pharmaceutical protein target and drug discovery.

Technology
DNANO's technology is based on a number of inventions from Cornell involving DNA amplification mediums and techniques.

Cornell Connection
The protein production platform that is the basis for P-Gel was invented by Dr. Dan Luo, College of Agriculture and Life Sciences.

Business
e2e Materials, LLC produces petroleum-free, biodegradable composites that are stronger, lighter, and cheaper than composites filling landfills today. Their composite material platform is as strong as midrange steels but is made from annually renewable resources including soy proteins and natural fibers such as bamboo, jute, flax and kenaf.

Technology
e2e's biodegradable composites are based on a method for creating biodegradable fibers and resins based on soy proteins that was developed at Cornell.

Cornell Connection
The inventor of the method e2e uses is Anil Netravali, College of Human Ecology.

Business
Acquired by Plant Health Care, Inc.

Business
Etron, Inc. develops, manufacturers, & markets microcomputer control systems for dairy farms.

Technology
Etron’s control system is based on a Cornell invention for a variable-speed-drive controller which optimizes vacuum level control in both milking and clean-in-place system washing phases. The apparatus significantly reduces electrical energy usage and cost.

Cornell Connection
The enabling invention for Etron was developed at Cornell by David Ludington, College of Agriculture and Life Sciences.

Business
Fingerlakes Aquaculture, Inc. is a large-scale producer of branded, farm-raised fish. They use an environmentally friendly indoor recirculating aquaculture system ("RAS") to produce fresh tilapia that can be eaten by customers within hours of the fish leaving the facility. Their production facility in Groton, New York produces tilapia that serves customers throughout the Eastern United States and Canada. The production facility utilizes patented Aquafilter technology, which lowers costs, making Fingerlakes one of the most efficient producers of fish in North America.

Technology
Fingerlakes Aquaculture's business is based on Cornell inventions for a method to fortify the diet of tilapia with omega-3 fatty acids, and a water re-circulating system.

Cornell Connection
The methods underlying Fingerlakes Aquaculture's tilapia raising were invented by Michael Timmons, College of Engineering, and Rui Hai Liu, College of Agriculture and Life Sciences

Business
Gene Network Sciences, Inc. (GNS) is a privately held biosimulation company with offices in Cambridge, Massachusetts, and Ithaca, New York. Founded in 2000, GNS creates data-driven and quantitative compound simulation models that help pharmaceutical companies become much more confident in their drugs' eventual success in the face of sparse late-stage pipelines, low clinical trial success rates, and budget cuts. GNS creates simulation models though amulti-disciplinary technological approach that embodies the molecular biology, computer science, mathematics, genetics, chemical engineering and physics.

Business
GenVec, Inc. is a biopharmaceutical company developing novel therapeutic drugs and vaccines. GenVec's lead product, TNFerade, is currently in a pivotal clinical study (PACT) in locally advanced pancreatic cancer. Additional clinical trials are in progress in rectal cancer, head and neck cancer and melanoma. GenVec also uses its proprietary adenovector technology to develop vaccines for infectious diseases including HIV, malaria, foot-and-mouth disease, respiratory syncytial virus (RSV), HSV-2, and influenza.

Technology
GenVec utilizes over 20 Cornell technologies and methods involving gene therapy in its therapeutic products.

Cornell Connection
Cornell inventors are Ronald Crystal, Todd Rosengart, and Erik Falck-Pederson of Cornell Weill Medical College.

Business
Hybrid Silica Technologies, Inc. (HST) develops "green" nanostructured silica materials with particular emphasis on fluorescent core-shell silica nanoparticles ("C dots"). These advanced materials have great potential in bioimaging, diagnostics, value-added devices such as sensors, development tools for drug discovery and other related areas in the life sciences and beyond. HST has focused on applications such as intra-operative visualization for cancer surgery. Working together with Cornell University, HST's research team is developing C dots for injection into the bloodstream to help surgeons ensure complete removal of cancerous tissues.

Technology
C Dots are based on amorphous silica (SiO2), which is found in foods, pharmaceuticals and nutraceuticals. The Company has synthesized C dots as small as 10 nm. If surface treated with the appropriate coatings, these materials are stable under physiological conditions. The Company has also developed coatings to make the C dots biocompatible. C dots are being investigated in joint research programs at Cornell University's Ithaca campus and at its Weill Medical College in New York City as well as at numerous other high-profile research institutions including Memorial Sloan-Kettering Center, the National Cancer Institute and the Massachusetts Institute of Technology.

Cornell Connection
Dr. Ulrich Wiesner and Dr. Hooisweng Ow, College of Engineering invented C dots.

Business
Hµrel develops bioanalytic devices called "HµRELs" that are used in pharmaceutical development and industrial and consumer product safety testing. A Hµrel is a microfluidic circuit that models real-time protein binding, metabolism and extraction in the liver. Hµrels have the potential to provide drug companies with data early in the preclinical phase so they can "fail early" in vitro and make corrections before they go into animal studies. Hµrel estimates that their Hµrels can save one eighth of the cost of bringing a drug to market (drug companies spend roughly $800 million on average to gain FDA approval).

Technology
Originally developed at Cornell University, HµRELs are patented microfluidic circuits that can reveal interactions among multiple tissue types and one or more pharmacologic compounds.

Cornell Connection
The Cornell inventor of HµRELs is Michael Shuler, College of Engineering.

Business
intElect Medical develops and commercializes neurostimulation systems for improving the recovery of brain injury patients. Two percent of the U.S. population suffers from Traumatic Brain Injury (TBI) and each year, 1.4 million new Americans sustain a traumatic brain injury. intElect's deep brain stimulation therapy has been initially proposed for the treatment of patients who are in a minimally conscious state (MCS) or have chronic severe cognitive disability. intElect recently received series B financing for $7 million from Boston Scientific Corp. (NYSE: BSX) and Greatbatch, Inc. (NYSE: GB).

Technology
intElect Medical's methodology is based on methods developed at Weill Cornell Medical College for using precise electrical pulses to improve neurological function and cognitive function and/or coordination of function.

Cornell Connection
THE DBS therapy was invented by Nicholas D. Schiff, Weill Medical College of Cornell University.

Business
Jodange creates a web-based service called "Top of Mind," that finds opinions in digitized text and tracks them over time. The company's patent pending, natural language processing engine determines the opinion holder, the topic, and the sentiment (positive, neutral, or negative) for each opinion, allowing users to search for opinions along any of these dimensions. Initially targeting the financial services industry, "Top of Mind" draws on hundreds of thousands of documents tracking the Fortune 1000 and S&P 500, including annual financial reports, transcripts of quarterly calls, CEO presentations, analyst reports and financial blogs. Its focus will be extended over time to encompass more general information found on the web and in other content sources.

Technology
Jodange's opinion search tool is based on natural language processing algorithms developed at Cornell that comprise an "Opinion Summarization System."

Cornell Connection
Claire Cardie, College of Engineering, and her Phd students developed the algorithms that are the basis for "Top of Mind."

Business
Kionix is a global leader in the design and manufacturing of high-performance, silicon-micromachined, MEMS inertial sensors. The Company's products enable a variety of applications in the consumer electronics, industrial, health care, and automotive markets to include motion-based gaming, user-interface functionality in mobile handsets, inertial navigation and dead reckoning, and hard disk drive drop protection in mobile products.

Technology
Kionix's motion sensors are based on more than 30 Cornell technologies that involve MEMS and motion sensing.

Cornell Connection
The founding technology for Kionix was developed by former Cornell University engineering professor Noel MacDonald, PhD.

Business
The average American eats one apple every five or six days, not enough to provide health benefits. Compared to apple flesh, apple skins contain 2-6 times more dietary phytochemicals which can act as disease fighting antioxidants. Appleboost Products, Inc. develops and market retail products that incorporate apple peel powder. Presently, the company sells a 270ct. bottle of capsules and a line of specialty Certified Organic applesauce tubes(32g) that are offered in two flavors, Wildberry and Peach Mango.

Technology
AppleBoost™ is based on techniques developed at Cornell University that refined apple peel powder processing techniques. The resulting apple peel powder retains and yields extraordinary levels of phenolics, enabling consumers to reap the tremendous health benefits associated with apple peels.

Cornell Connection
Licensed founding method was developed by Rui Hai Liu, College of Agriculture and Life Sciences.

Business
Metabolon provides global biochemical profiling services (metabolomics) for pharmaceutical, biotech, bioprocessing, agriculture, cosmetic and consumer product research. Metabolomics is the identification and quantitation of the biochemicals from nearly any type of sample. Metabolon’s platform provides a global analysis of complex biological samples for the discovery of markers and pathways associated with drug action or disease. This metabolomics-driven approach enables the identification of biomarkers useful for the development of a wide range of diagnostics and provides insight into complex biochemical processes such as drug action, toxicology and bioprocess optimization.

Technology
Metabolon's technology for using metabolomics to detect and quantify small molecules present in cells was partially based on a patent licensed from Cornell.

Cornell Connection
Dr. Bruce Kristal of the Weill Cornell Medical College helped to develop the methodology that helped shape Metabolon's founding metabolomic experiments.

Business
Mezmeriz uses carbon fiber MEMS technology developed at Cornell to make a high-definition projector that is the size of a matchbook. They are currently building a prototype of the company's technology, which will ultimately lead to a projection system that can be embedded into any mobile device.

Technology
Mezmeriz offers an updated MEMS, or micro-electronic mechanical system, to replace traditional silicon lattices with carbon fiber. This way, their MEMS can produce a vibrating resonance engine that has the benefits of a silicon manufacturing, but with the strength advantages of carbon fiber.

Cornell Connection
Shahyaan Desai, College of Human Ecology, and Michael Thompson, College of Engineering, invented the various MEMS-based technologies that will be used in displays.

Business
MiteGen develops and manufactures a number of products and tools that determine the structure and crystallization of proteins, viruses, and pharmaceutical compounds. MiteGen's target customers are academic and government laboratories and pharmaceutical companies.

Technology
MiteGen's tools are based on technologies developed at Cornell for a system for crystal growth, and a method for manipulating and mounting crystals for X-ray crystallography and structure determination.

Cornell Connection
MiteGen's founding technologies were developed by Robert Thorne, College of Engineering.

Business
Nano Surfaces Inc (NSI) produces environmentally friendly coatings that are less costly and more effective than traditional toxic tributyltin coatings. NSI's coatings address the demands of the antifouling, antimicrobial, and anticorrosion markets; NSI is ramping up to commercialize marine antifouling coatings.

Technology
Nano Surfaces technology is based on polymer coatings developed at Cornell University.

Cornell Connection
Professor Chris Ober, College of Engineering

Business
Novomer develops two types of "green" polymers: both are biodegradable polymers that are less polluting than traditional plastics. The first are made using carbon dioxide and the second are made using carbon monoxide as feedstocks. Novomer's method uses catalysts developed at Cornell to develop polymers whose feedstocks contain between 30 and 50 percent carbon monoxide and carbon dioxide; in comparison, most plastics are produced using 100% petroleum products as their primary ingredient.

Technology
Novomer, Inc. is founded on novel catalytic technologies developed by Dr. Geoffrey Coates in the Department of Chemistry and Chemical Biology at Cornell.

Cornell Connection
Dr. Geoffrey Coates, College of Engineering.

Business
OPTIGEN is a service company established to provide DNA-based diagnoses and information about inherited diseases of dogs.

Technology
The company's core technology is genetic tests in the area of inherited eye diseases involving retinal degeneration.

Cornell Connection
OPTIGEN's initial testing services were based upon the discoveries made by Gustavo Aguirre (now at the University of Pennsylvania) and Gregory Acland, Cornell University, College of Veterinary Medicine.

Business
Phytex is a joint venture company that is majority owned by JBS United. Phytex, LLC produces enzymes for the animal feed market that go into OptiPhos, a feed product for livestock. OptiPhos is based on phytase, an enzyme that releases three times more phosphorus from feed grain in poultry, and nearly two times more in pigs. Optiphos offers an enhanced diet for animals since inorganic phosphate is replaced by energy that can be metabolized; also, Optiphos creates substantially less phosphorus in the animals' waste.

Technology
OptiPhos is based on a phytase gene that was developed at Cornell University.

Cornell Connection
The founding technology for Phytex was created by Xingen Lei, College of Agriculture and Life Sciences.

Business
Q Therapeutics develops neural stem cell based therapeutic products for debilitating diseases of the central nervous system (CNS). Q's initial development efforts are focused on natural cell-based products that regenerate insulating myelin on damaged neurons, with the goal of restoring normal neuron function. Q's first product, Q-Cells®, is designed to address a wide range of diseases, including multiple sclerosis (MS), transverse myelitis, cerebral palsy, spinal cord injury, and certain types of stroke.

Technology
Q-Cells® are glial progenitor cells and their progeny, purified from various tissue sources.

Cornell Connection
Stem cell discoveries covering certain cells of the CNS made at Weill Cornell Medical College by Steven Goldman have contributed to Q's broad patent portfolio.

Business
Re-Markable Paint produces eco-friendly temporary marketing paint and paint-remover for athletic fields. Re-Markable Paint produces formulas for both natural grass and artificial turf.

Technology
Re-Markable Paint's products are based on research at Cornell focusing on polymers and surface coatings.

Cornell Connection
The research underlying Re-Markable paint was created by D. Tyler McQuade, College of Arts and Sciences and Frank Rossi, College of Agriculture and Life Sciences.

Business
Merged with and became part of RF MicroDevices in 2001.

Business
Acquired by Dupont.

Business
Terrenew manufactures products to absorb oil and other liquid spills. Terrenew has three products: granulate-based OilMaster7X made of manure, pad-based OilMaster7X made of manure, and MetalMaster, which absorbs heavy metals from solutions. Terrenew's products are made from different agricultural wastes including tree bark and/or processed, dried cow manure.

Technology
Terrenews's products are based on methods that were developed at Cornell for absorbing oil and other liquid spills, and removing heavy metals from contaminated groundwater or industrial process water.

Cornell Connection
The founding methodology for Terrenew was invented by Gary Harman and Terry Spittler, College of Agriculture and Life Sciences.

Business
Veratag is an early-stage company whose mission is to provide virtually absolute security in radio frequency identification (RFID) and other electronic security applications. The innovation is the use of microelectromechanical systems (MEMS), what Veratag calls MEMflakes™, which produce unique analog signals for identification, authentication, and counterfeit prevention. MEMflakes™, like snowflakes, are all unique so each MEMflake™ is essentially uncloneable, making them ideal for access control, identification cards, anti-counterfeiting applications, and in electronic lock and key systems.

Technology
Veratag's MEMflakes™ are based on MEMS technology developed at Cornell. MEMflakes™ use resonant signatures, similar to voiceprints, for identification, authentication, and anti-counterfeiting applications.

Cornell Connection
Basic research that led to the IP licensed by Veratag from Cornell was developed in the research group of Harold Craighead, College of Engineering.