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2009

Patent Patent Number Innovators
Enhancing Neurotrophin-Induced Neurogenesis by Endogenous Neural Progenitor Cells by Concurrent Overexpression of Brain Derived Neurotrophic Factor and an Inhibitor of a Prog-Gliogenci Bone Morphogenetic Protein7,576,065Eva Chmielnicki, Aris Economides, Steven A. Goldman
Methods for Preventing Mitochndrial Permeability Transition7,576,061Hazel H. Szeto, Peter Schiller, Kesheng Zhao
Recombinant Bifunctional Protein of Human Lutropin Receptor and Human Chorionic Gonadotropin B-Subunit and Uses Thereof7,563,612Premila Rathnam, Meirong Hao, Brij Saxena, Mukul Singh
Detection of Nucleic Acid Sequence Differences Using Coupled Ligase Detection and Polymerase Chain Reactions 7,556,924George Barany, Robert P. Hammer, Francis Barany, Matthew Lubin
Methods for Reducing Oxidative Damage7,550,439Hazel H. Szeto
Methods for Drug Discovery, Disease Treatment and Diagnosis Using Metabolomics7,550,260Rima Kaddurah-Daouk, Bruce S. Kristal
Methods for Drug Discovery, Disease Treatment and Diagnosis Using Metabolomics7,550,258Rima Kaddurah-Daouk, Bruce S. Kristal
System and Method for Generating Composite Subtraction Images for Magnetic Resonance Imaging7,545,967Ramin Zabih, Martin R. Prince, Junhwan Kim, Jeff Bezanson, Hale Ersoy, Yi Wang, Richard Watts
Methods for Reducing CD36 Expression7,541,340Hazel H. Szeto, Shaoyi Liu, Sunghee Cho
Feedback Mechanism for Deep Brain Stimulation7,539,543Nicholas D. Schiff, Keith Purpura, Steven Kalik
Platelet-Derived Growth Factor Protection of Cardiac Myocardium7,514,261Shahin Rafii, Jay Edelberg, Mun K. Hong
Methods of Treating Prostate Cancer with Anti-Prostate Specific Membrance Antigen Antibodies7,514,078Neil H. Bander, Frank J. Carr, Anita Hamilton
High Affinity Ligand for p75 Neurotrophin Receptor7,507,799Barbara Hempstead, Ramee Lee, Kenneth K Teng, Pouneh Kermani
Protection of Cardiac Myocardium7,504,379Jay Edelberg, Munira Xaymardan
System, Method and Apparatus for Small Pulmonary Nodule Computer Aided Diagnosis from Computed Tomography Scans7,499,578Anthony P. Reeves, Claudia Henschke, David Yankelevitz, Antoni Chan
Medicinal Uses of Mu-Opioid Receptor Agonists7,498,297Hazel H. Szeto, Peter Schiller
Rapidly Cleavable Sumo Fusion Protein Expression System for Difficult to Express Proteins7,498,165Christopher D. Lima, Elena Nossessova
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2008

Patent Patent Number Innovators
Macroencapuslated Secretory CellRE40,555Albert L. Rubin, R. Jain
A Method for Isolating and Purifying Multipotential Neural Progenitor Cells and Multipotential Neural Progenitor Cells7,468,277Hideyuki Okano, Steven A. Goldman
Method of Designing Addressable Array for Detection of Nucleic Acid Sequence Differences Using Ligase Detection Reaction7,455,965Monib Zirvi, Reyna Favis, Richard Kliman, Francis Barany, Norman P. Gerry
Treating Disorders of the Nervous System7,439,328Ching-Hwa Sung, Jen-Zen Chuang
Detection of Nucleic Acid Sequence Differences Using Coupled Ligase Detection and Polymerase Chain Reactions7,429,453Robert P. Hammer, Francis Barany, Matthew Lubin, George Barany
Use of Proephithelin to Promote Wound Repair and Reduce Inflammation7,427,595Aihao Ding, Carl F. Nathan, Jing Zhu
Method and System for Analyzing Multi- Variate Data Using Canonical Decompostion7,409,321Michael Repucci, Nicholas D. Schiff, Jonathan D. Victor
Stem Cell-Specific Promoters and Their Use7,396,680Jun Lin, Shahin Rafii, Sergey V. Shmelkov
Alternatively Spliced Nucleic Acid Molecules7,368,553Ronald G. Crystal, Neil R. Hackett
Detection of Nucleic Acid Sequence Differences Using Coupled Ligase Detection and Polymerase Chain Reactions7,364,858George Barany, Robert P. Hammer, Francis Barany, Matthew Lubin
Method for Detection of Promoter Methylation Status7,358,048Yu-Wei Tim Cheng, Carrie Shawber, Francis Barany
Isolated Nucleic Acid Molecules Encoding Cancer Associated Antigens, the Antigens er se, and Uses Thereof7,354,992Lloyd J. Old, Elke Jager, Matthew Scanlan, Yao-Tseng Chen, Alexander Knuth, Ali Gure, Dirk Jager, Elisabeth Stockert
Detecting Recurrent Vulvovaginal Candidiasis or Vulvar Vestibulitis Syndrome and Method for Treating Same7,335,633Steven Witkin
Detection of Nucleic Acid Sequence Differences Using Coupled Ligase Detection and Polymerase Chain Reactions7,332,285Robert P. Hammer, Francis Barany, Matthew Lubin, George Barany
Methods for Drug Discovery, Disease Treatment and Diagnosis Using Metabolomics7,329,489Rima Kaddurah-Daouk, Bruce S. Kristal
Detection of Nucleic Acid Sequence Differences Using Coupled Ligase Detection and Polymerase Chain Reactions7,320,865Robert P. Hammer, Francis Barany, Matthew Lubin, George Barany
Small Cell Lung Cancer Associated Antigens and Uses Therefor7,314,721Lloyd J. Old, Matthew Scanlan, Ivan Gout, Yao-Tseng Chen, Ali Gure, Elisabeth Stockert
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2007

Patent Patent Number Innovators
Macroencapuslated Secretory CellRE39,542Albert L. Rubin, Kanti Jain, Barry Smith, R. Jain
Adaptive Diastolic Interval Control of Action Potential Duration Alternans7,313,437Peter Nicholas Jordan, David J. Christini
Detection of Nucleic Acid Sequence Differences Using Coupled Ligase Detection and Polymerase Chain Reactions7,312,039George Barany, Robert P. Hammer, Francis Barany, Matthew Lubin
Prokaryotic Proteasomal Proteases of Mycobacterium Tuberculosis (MTB) as Targets for Antibiotic Therapy7,282,491Carl F. Nathan, Katerina H. Darwin
System and Method for Three-Dimensional Image Rendering and Analysis7,274,810Anthony P. Reeves, William J. Kostis, Claudia Henschke, David Yankelevitz
Methods of Inhibiting Platelet Activation and Recruitment7,264,809C. Maliszewski, Richard Gayle, Aaron J. Marcus
Adenoviral Vector with Replication-Dependent Transgene Expression7,261,885Erik S. Falck-Pedersen, Jason Gall
High Fidelity Detection of Nucleic Acid Differences by Ligase Detection Reaction7,244,831Jane (Jianying) Luo, Marilyn Khanna, Donald Bergstrom, Francis Barany
Blocking Leukocyte Emigration and Inflammation by Interfering with CD99/HEC27,223,395Alan R. Schenkel, William A. Muller
Detection of Nucleic Acid Differences Using Combined Endonuclease Cleavage and Ligation Reactions7,198,894Francis Barany, Weiguo Cao, Jianmin Huang, Jing Lu
Methods & Compositons for Treating or Preventing Skin Disorders Using Binding Agents Specific for Prostate Specific Membrane Antigen7,192,586Neil H. Bander
Electrofusion Microelectrode7,186,547Gianpiero D. Palermo
Use of PPARy Ligands to Treat Human Papillomavirus-Induced Disease7,183,316Kotha Subbaramaiah, Andrew Dannenberg
An Antigen for Developing Neutralizing Antibodies to Human Immunodeficiency Virus7,179,468Min Lu, Hong Ji
Canonical Decomposition for Analysis of Multichannel Data7,171,339Michael Repucci, Nicholas D. Schiff, Jonathan D. Victor
Detection of Nucleic Acid Sequence Differences Using Coupled Ligase Detection and Polymerase Chain Reactions7,166,434Robert P. Hammer, Francis Barany, Matthew Lubin, George Barany
Treatment and Diagnosis of Cancer7,163,680Neil H. Bander
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2006

Patent Patent Number Innovators
Telomerase Immortalized Human Neural Stem Cells and Phenotypically-Restricted Progenitor Cells7,150,989Steven A. Goldman, Neeta S. Roy
Endothelial Precursor Cells for Enhancing and Restoring Vascular Function7,135,171Shahin Rafii, Jay Edelberg, Mun K. Hong, Robert P. Lanza, Michael D. West
Motion Organized Simultaneous Acquisiton with Interactive Control for Fast Real-Time Navigator Guided Imaging7,123,757Ramin Zabih, Yi Wang, Vladimir N. Kolmogorov
Isolated Nucleic Acid Molecule Encoding an Esophageal Cancer Associated Antigen,The Antigen Itself, & Use Thereof7,115,729Lloyd J. Old, Ugur Sahin, Oziem Tureci, Elke Jager, Matthew Scanlan, Michael Pfreundschuh, Jan W. Drijfhout, Yao-Tseng Chen, Alexander Knuth, Ali Gure
Treatment and Diagnosis of Prostate Cancer7,112,412Neil H. Bander
Electrofusion Microelectrode 7,101,703Gianpiero D. Palermo
Detection of Nucleic Acid Sequence Differences Using Coupled Ligase Detection/Con7,097,980Robert P. Hammer, Francis Barany, Matthew Lubin, Phillip Belgrader, George Barany
Method of Treating Polycythemia Vera7,094,785Richard T. Silver
Detection of Nucleic Acid Sequence Differences Using the Ligase Detection Reaction with Addressable Arrays7,083,917Monib Zirvi, Robert P. Hammer, Francis Barany, Herman Blok, Maria Kempe, George Barany
Precision Ultrasound Measurement For Intraocular Lens Placement7,048,690Donald Jackson Coleman, Mark J. Rondeau, Ronald H. Silverman
Modified Antibodies to Prostate-Specific Membrane Antigen and Uses Thereof7,045,605Neil H. Bander, Frank J. Carr, Anita Hamilton
Cyclooxygenase-1 Inhibition7,041,694Andrew Dannenberg
Method of Inducting Neuronal Production in the Brain and Spinal Cord7,037,493Abdel-latif Benraiss, Steven A. Goldman
Protective Immunity or Immunological Tolerance Induced with RNA, Particularly Total Cellular RNA7,015,204Richard D. Granstein
Coupled Polymerase Chain Reaction-Restriction Endonuclease Digestion-Ligase Detection Reaction Process7,014,994Robert P. Hammer, Donald Bergstrom, Francis Barany, Joseph P Day
Isolated Peptides Which Bind to HLA-C Molecules and Uses Thereof7,009,035Lloyd J. Old, Elke Jager , Sache Gnjatic, Y. Nagata, Yao-Tseng Chen, Alexander Knuth
Methods for Drug Discovery, Disease Treatment, and Diagnosis Using Metabolomics7,005,255Rima Kaddurah-Daouk, Bruce S. Kristal
Method and Apparatus for Anatomically Tailored K-Space Sampling and Recessed Elliptical View Ordering for Bolus-Enhanced 3D MR Angiography7,003,343Martin R. Prince, Yi Wang, Richard Watts
Isolated Nucleic Acid Molecules Associated with Colon Cancer and Methods for Diagnosing and Treating Colon Cancer6,982,316Yao-Tseng Chen, Ludwig Institute for Cancer Research
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2005

Patent Patent Number Innovators
Methods for Designing Specific Ion Channel Blockers6,979,547Xin-Yun Huang
Reversing or Preventing Premature Vascular Senescence6,967,219Steven S. Gross, Michael Goligorsky
Methods and Compositions for Inhibiting HIV Infectivity6,964,763Jeffrey Laurence, Ralph L. Nachman, Rene Crombie
High Fidelity Thermostable Ligase & Uses Thereof6,949,370Francis Barany, Weiguo Cao, Jie Tong
Method of Enhancing Bone Density 6,939,540Imre Kovesdi, Ronald G. Crystal, Chisa Hidaka, Ohene Boachie-Adjei, Bernard A. Rawlins
Low Dose Interleukin 2 Therapy6,921,530Kendall A. Smith
Intracardiac Detection and Control of T-Wave Repolarization Alternans6,915,156David J. Christini, Bruce Lerman, Kenneth M. Stein
Isolated Nucleic Acid Molecules Encoding Cancer Associated Antigens, The Antigens per se, and Uses Thereof6,911,529Matthew Scanlan, Elke Jager, Yao-tseng Chen, Alexander Knuth, Ali Gure, Elizabeth Stockert, Lloyd Old, Dirk Jager
Measurement of Protective Genes in Allograft Rejection (Previously D-2221-05)6,900,015Ma Nali, Christiane Ferran, Miguel C. Soares, Manikkam Suthanthiran, Yingyos Avihingsanon, Terry Strom
Method & Compositions for Reducing Cardiac Dysfunctions with a Selective Histamine H3 Receptor Agonist6,884,809Roberto Levi, Randi B. Silver
Diagnosis of Normal Pressure Hydrocephalus by Automated Post Processing of MR Images6,882,876Aziz M. Ulug
DNA Polymerase III Holoenzyme 6,875,852Michael O'Donnell
Rapidly Cleavable SUMO Fusion Protein Expression System for Difficult to Express Proteins6,872,551Christopher D. Lima, Elena Mossessova
Purified Populations of Stem Cells6,852,533 Larry Witte, Shahin Rafii, Malcolm A.S. Moore
Detection of Nucleic Acid Sequence Differences Using the Ligase Detection Reaction with Addressable Arrays6,852,487Monib Zirvi, Robert P. Hammer, Francis Barany, Herman Blok, Maria Kempe, George Barany
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2004

Patent Patent Number Innovators
CT76,830,924Solam Tsang, Elke Jager, Yao-Tseng Chen, Alexander Knuth, Ali Gure, Elisabeth Stockert, Lloyd J. Old
IgM Antibodies to the 70 kDa Heat Shock Protiein as a Marker for Cytomegalovirus Infection6,828,113Steven Witkin
Adenovirus Gene Expression System6,824,770Erik S. Falck-Pedersen
Anti-Amyloid Peptide Antibody Based Diagnosis and Treatment of a Neurological Disease or Disorder6,815,175Paul Szabo, Marc E. Weksler
Discovery, Localization, Harvest and Propagation of an FGF2 and BDNF-Responsive Population of Neural and Neuronal Progenitor Cells in the Adult Human Forebrain6,812,027Steven A. Goldman, Maiken Nedergaard
Detection of Nucleic Acid Sequence Differences Using Coupled Ligase Detection and Polymerase Chain Reactions6,797,470Robert P. Hammer, Francis Barany, Matthew Lubin, George Barany
SEREX - Colon Diagnosis6,794,501 Matthew Scanlan, Yao-Tseng Chen, Elisabeth Stockert, Lloyd J. Old
Method and Apparatus for Measuring and Correcting Motion Effects Using Navigator Echoes6,791,323Thanh D. Nguyen, Yi Wang
Pharmacotherapy for Vascular Dysfunction Associated with Deficient Nitric Oxide Bioactivity6,784,178Steven S. Gross, Caroline L. Jones
Isolated Nucleic Acid Molecules Encoding Cancer Associated Antigens, the Antigens er se, and Uses Thereof6,774,226Matthew Scanlan, Elke Jager, Yao-tseng Chen, Alexander Knuth, Ali Cure, Elizabeth Stockert, Lloyd Old, Dirk Jager
Treatment and Diagnosis of Cancer6,770,450Neil H. Bander
Treatment and Diagnosis of Prostate Cancer6,767,711Neil H. Bander
Automatic Detection of Pulmonary Nodules on Volmetric Computed Tomography Images Using a Local Density Maximum Algorithm6,728,334Binsheng Zhao
Antibodies Which Bind to NY-ESO-1 Cancer Associated Proteins, Uses Thereof Truncated Forms of NY-ESO-1, & HLA..6,723,832Elke Jager, Matthew Scanlan, Yao-Tseng Chen, Alexander Knuth, Jan W. Drijfhout, Ali Gure, Lloyd J. Old, Gerd Ritter
hCG-hLH Receptor and hCG-hLH Receptor-hCG Complex as Antigens, Antibodies Thereto and Contraceptive Vaccine6,723,556Premila Rathnam, Brij Saxena
Detection of Epithelial Cell Cancers and Precancerous Condition6,706,506Lorraine J. Gudas, Xiaojia Sasha Guo
Compounds Useful in Pain Management6,703,483Hazel H. Szeto, Peter Schiller
Method for Separating Cells6,692,957Hong Wu, Steven A. Goldman
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2003

Patent Patent Number Innovators
Macroencapuslated Secretory CellRE38,027Albert L. Rubin, Kanti Jain, Barry Smith, R. Jain
REM Sleep Augmentation with Extraocular Light6,669,627Scott S. Campbell, Patricia J. Murphy
A Method for Isolation of Prostatic Epithelial Cells from Semen6,653,129Neil H. Bander, Leonard M. Glode, Chang I. Suh
Enhanced Biologically Based Chronotropic Biosensing6,650,919Jay Edelberg, David J. Christini
Treatment and Diagnosis of Cancer6,649,163Neil H. Bander
Use of Angiotensin II Inhibitors to Prevent Malignancies Associated with Immunosuppression6,641,811Mary Malucco, Manikkam Suthanthiran
Adenoviral Vectors with Tandem Fiber Proteins6,599,737Erik S. Falck-Pedersen
Sort Stream Stabilizer for Flow Cytometer 6,587,203Christopher Colon
Isolated Nucleic Acid Molecule Encoding Cancer Associated Antigen, The Antigen Itself, and Uses Thereof6,576,756Lloyd J. Old, Solam Tsang, Elke Jager, Yao-Tseng Chen, Alexlander Knuth, Ali Gure, Elisabeth Stockert
Chimeric Adenoviral Fiber Protein6,576,456Imre Kovesdi, Thomas J. Wickham, Joseph T. Bruder, Petrus W. Roelvink, Erik S. Falck-Pedersen, Jason Gall
High Fidelity Detection of Nucleic Acid Differences by Ligase Detection Reaction6,576,453Jane (Jianying) Luo, Marilyn Khanna, Donald Bergstrom, Francis Barany
Methodology for Predicting and/or Diagnosing Disease6,558,955Wayne Matson, Paul Milbury, Bruce S. Kristal
Method for Amplifying and Sequencing Nucleic Acid Molecules Using a Three Component Polymerase6,555,349Michael O'Donnell
(CAG)/Q expansion disorders6,548,243Arthur J. Cooper, John P. Blass
SSX Expression Assay6,548,064Georg Rammensee, Stefan Stevanovic, Yao-Tseng Chen, Ludwig Institute for Cancer Research
Method for Assessing Blood Flow and Apparatus Thereof6,547,731Donald Jackson Coleman, Ronald H. Silverman, Kathy Ferrara, Dustin Kruse
Mammalian Soluble Adenylyl Cyclase6,544,768Lonny R. Levin, Jochen Buck
Feedback Mechanism for Deep Brain Stimulation6,539,263Nicholas D. Schiff, Keith Purpura, Steven Kalik
Accelerating Identification of Single Nucleotide Polymorphisms & Alignment of Clones in Genomic Sequencing6,534,293Monib Zirvi, Jianzhao Liu, Brian W. Kirk, Francis Barany, Norman P. Gerry, Philip B. Paty
Method for Determining Status of a Cancerous Condition by Determining Antibodies to NY-ESO-1 in a Patient Sample6,525,177Elke Jager, Matthew Scanlan, Yao-Tseng Chen, Alexander Knuth, Elisabeth Stockert, Lloyd J. Old
A Method of Inhibiting an Immune Response to a Recombinant Vector6,525,029Keith B. Elkon, Erik S. Falck-Pedersen
Multiple Site Delivery of Adenoviral Vector for the Induction of Angiogenesis6,518,255Ronald G. Crystal, Todd K. Rosengart
Isolated Nucleic Acid Molecules Associated with Colon Cancer and Methods for Diagnosing and Treating Colon Cancer6,517,837Yao-Tseng Chen, Ludwig Institute for Cancer Research
Stimulation of Immune Response with Low Doses of Cytokines6,509,313Kendall A. Smith
DNA Molecule Encoding for Cellular Uptake of Mycobacterium Tuberculosis and Uses Thereof6,509,151Lee W. Riley
Remote Sensing Gene Therapy Delivery Device6,508,802Ronald G. Crystal, Todd K. Rosengart
Isolated Peptides Which Bind to HLA-C Molecules and Uses Thereof6,506,875Elke Jager , Yao-Tseng Chen, Sache Gnjatic, Y. Nagata, Alexander Knuth, Lloyd J. Old
Detection of Nucleic Acid Sequence Differences Using the Ligase Detection Reaction with Addressable Arrays6,506,594Robert P. Hammer, Francis Barany, Nancy E. Witkowski, Joseph P. Day, Norman P. Gerry, George Barany
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2002

Patent Patent Number Innovators
Methods and Compounds for Treating Autoimmune and Vascular Disease6,491,922John L. Ho
Treating Inflammatory Diseases of the Head and Neck with Cyclooxygenase-2 Inhibitors6,486,203Andrew Dannenberg
Enhanced Reverse Transcriptase Polymerase Chain Assay to Detect MN in Patients with Renal Cell Carcinoma6,451,532James M. McKiernan, Neil H. Bander, Ihor S. Sawczuk, Ralph Buttyan
Isolated Nucleic Acid Molecules Encoding Cancer Associated Antigens, the Antigens per se, and Uses Thereof6,448,073Matthew Scanlan, Elke Jager, Yao-Tseng Chen, Alexlander Knuth, Ali Gure, Elisabeth Stockert, Lloyd J. Old, Dirk Jager
Renal Cancer Assoicated Antigens & Uses Therefor6,440,663Lloyd J. Old, Elke Jager, Matthew Scanlan, Yao-Tseng Chen, Alexander Knuth, Elisabeth Stockert
Mammalian and Human REC2 6,410,226William K. Holloman, Michael C. Rice, Sheryl T. Smith, Shu Zhigang, Eric B. Kmiec
Human Actin Regulatory Proteins and Methods for Detection, Diagnosis & Treatment of Different Stages of Carcinogenesis 6,403,766Joel D. Pardee
Cox-2 Breast Cancer Treatment6,403,630Kotha Subbaramaiah, Andrew Dannenberg
Isolated Nucleic Acid Molecules Associated with Colon, Renal & Stomach Cancer & Methods of Using These6,403,373Matthew Scanlan, Yao-Tseng Chen, Elisabeth Stockert, Lloyd J. Old
DNA Molecule Encoding for Cellular Uptake of Mycobacterium Tuberculosis and Uses Thereof 6,399,764Lee W. Riley
SSX6,339,140Solam Tsang, Ugar Sahin, Matthew Scanlan, Ozlem Tureci, Michael Pfreundschuh, Yao-Tseng Chen, Alexander Knuth, Ali Gure, Lloyd Old
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2001

Patent Patent Number Innovators
Method of Inducing Angiogenesis (Gradient Effect) 6,329,348Ronald G. Crystal, Todd K. Rosengart
Minimally Invasive Gene Therapy Delivery Device and Method 6,322,536Ronald G. Crystal, Todd K. Rosengart
Improved Corneal Scanning Method and Apparatus6,315,727Donald Jackson Coleman, Dan Z. Reinstein, Ronald H. Silverman
High Fidelity Detection of Nucleic Acid Differences by Ligase Detection Reaction 6,312,892Jane (Jianying) Luo, Marilyn Khanna, Donald Bergstrom, Francis Barany
CT76,297,364Tsang Solam, Elke Jager, Yao-Tseng Chen, Alexander Knuth, Ali Gure, Elisabeth Stockert, Lloyd J. Old
SSX6,291,658Solam Tsang, Ugar Sahin, Matthew Scanlan, Ozlem Tureci, Michael Pfreundschuh, Yao-Tseng Chen, Alexander Knuth, Ali Gure, Lloyd Old
Treating Cancers Associated with Overexpression of Class I Family of Receptor Tyrosine Kinases6,291,496Andrew Dannenberg, Kotha Subbaramaiah
SSX Expression Assay6,287,756Ugur Sahin, Oziem Tureci, Michael Pfreundschuh, Yao-Tseng Chen, Ali Gure, Lloyd J. Old
Human Origin of Replication Complex Gene and Uses Thereof6,281,347Irena Bruck, Frank Dean, Michael O'Donnell
Blocking Induction of Tetrahydrobiopterin to Block Induction of Nitric Oxide Synthesis6,274,581Steven S. Gross
Isolated Nucleic Acid Molecule Encoding an Esophageal Cancer Associated Antigen,The Antigen Itself, & Use Thereof6,274,145Ugur Sahin, Elke Jager, Matthew Scanlan, Yao-Tseng Chen, Oziem Tureci, Michael Pfreundschuh, Alexander Knuth, Jan W. Drijfhout, Ali Gure, Lloyd J. Old
Detection of Nucleic Acid Sequence Differences Using Coupled Ligase Detection and Polymerase Chain Reactions 6,268,148Robert P. Hammer, Francis Barany, Matthew Lubin, George Barany, Phillip Belgrader
Method for Determining Status of a Cancerous Condition by Determining Antibodies to NY-ESO-1 in a Patient Sample 6,255,470Matthew Scanlan, Yao-Tseng Chen, Ali Gure, Lloyd J. Old
Method for Determining Status of a Cancerous Condition by Determining Antibodies to NY-ESO-1 in a Patient Sample 6,251,603Elke Jager, Alexander Knuth, Elisabeth Stockert, Lloyd J. Old
Method for Separating Cells6,245,564Hong Wu, Steven A. Goldman
Treatments Based on Discovery that Nitric Oxide Synthase is a Paraquat Diaphorase6,231,894Steven S. Gross, Jonathan D. Stamler, Brian Day, Owen W. Griffith
Method for Performing Magnetic Resonance Angiography with Dynamic K-Space Sampling6,230,040Yi Wang, Howard M. Lee
DNA Molecule Fragments Encoding for Cellular Uptake to Mycobacterium Tuberculosis and Uses Thereof 6,224,881Lee W. Riley
Process for Reconstituting the Polymerase III & other Sub- Assemblies of DNA Polymerase III Holoenzyme from Peptide... 6,221,642Michael O'Donnell
Method of Screening Agents as Candidates for Drugs or Sources of Drugs6,200,760Andrew Dannenberg, David S. Pasco, Kotha Subbaramaiah
Coronary Magmetic Resonance Angiography Using Motion Matched Acquistion 6,198,959Yi Wang
Ultra-Short Acting Neuromuscular Blockers 6,187,789John Savarese, Eric Bigham, Grady Boswell, Roy Swaringen Jr., Sanjay S. Patel, Eric E. Boros, Robert A. Mook Jr., Vincente Samano
Methods of Evaluating Transplant Rejection6,187,534Manikkam Suthanthiran, Lauro Vasconcellos, Terry Strom
Substituted Isoquinolines as Ultra Short Acting Neuromuscular Blockers6,177,445John Savarese, Eric Bigham, Grady Boswell, Roy Swaringen Jr., Sanjay S. Patel, Eric E. Boros, Robert A. Mook Jr., Vincente Samano
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2000

Patent Patent Number Innovators
Method of Expressing an Exogenous Nucleic Acid6,165,754Ronald G. Crystal, Neil R. Hackett, Todd K. Rosengart, Xiaohuai Zhou
Method of Modulating Hair Growth 6,159,950Ronald G. Crystal, Noboru Sato, Phillip L. Leopold
Blocking Induction of Tetrahydrobiopterin to Block Induction of Nitric Oxide Synthesis6,153,615Steven S. Gross
Chimeric Adenoviral Coat Protein 6,153,435Thomas J. Wickham, Ronald G. Crystal, Erik S. Falck-Pedersen, Jason Gall, Imre Kovesdi
Treatment of Estrogen-Receptor Positive Breast Cancer and Estrogen-Receptor Negative Breast Cancer w/Retinoid with...6,150,421Lorraine J. Gudas, Fadila Derguini
CT Expression Assay for Breast Cancer6,140,050Ugur Sahin, Oziem Tureci, Yao-Tseng Chen, Michael Pfreundcshuh, Lloyd J. Old
Treatment and Diagnosis of Prostate Cancer6,136,311Neil H. Bander
Non-Ocular Circadian Clock Resetting in Humans6,135,117Scott S. Campbell, Patricia J. Murphy
Chimeric Adenoviral Coat Protein and Methods of Using Same 6,127,525Thomas J. Wickham, Ronald G. Crystal, Erik S. Falck-Pedersen, Jason Gall, Imre Kovesdi
Treatment and Diagnosis of Prostate Cancer 6,107,090Neil H. Bander
Proteins of Kaposi's Sarcoma Associated Herpesvirus6,093,806Ethel Cesarman, Daniel M. Knowles
Constitutively Active G Protein Coupled Receptor of HHV 8 & Method of Identifying Negative Antagonists of G Protein Coupled Receptors6,087,115Leandros Arvanitakis, Elizabeth Geras-Raaka, Marvin C. Gershengorn, Ethel Cesarman
Enhanced Reverse Transcriptase Polymerase Chain Assay to Detect MN in Patients with Renal Cell Carcinoma6,087,098James M. McKiernan, Neil H. Bander, Ihor S. Sawczuk, Ralph Buttyan
A Method for the Treatment of Fibroproliferative Disorders by Application of Inhibitors ofProtein Hydroxylation 6,080,766Timothy A. McCaffrey, Hartmut Hanauske-Abel, Robert Walter Grady
DNA Molecule Encoding for Cellular Uptake of Mycobacterium Tuberculosis and Uses Thereof 6,072,048Lee W. Riley
Isolated Nucleic Acid Molecule Encoding an Esophageal Cancer Assoicated Antigen,the Antigen Iselff & Use Thereof6,069,233Ugur Sahin, Matthew Scanlan, Yao-Tseng Chen, Oziem Tureci, Michael Pfreundschuh, Ali Gure, Lloyd J. Old
A Thermostable Ligase Mediated DNA Amplification System for the Detection of Genetic Diseases 6,054,564John A. Zebala, Francis Barany, Deborah Nickerson, Leroy Hood, Robert J. Kaiser
Method for the Treatment of Conditions Mediated by Collagen Formation Together with Cell Proliferation6,046,219Timothy A. McCaffrey, Hartmut Hanauske-Abel, Robert Walter Grady
Stimulation and/or Maintenance of Immune Response with Low Doses of IL-2 & Related Agents, Various Compositions... 6,045,788Kendall A. Smith
Isolated Nucleic Acid Molecules Associated with Colon Cancer & Methods for Diagnosing and Treating Colon Cancer6,043,084Matthew Scanlan, Yao-Tseng Chen, Elisabeth Stockert, Lloyd J. Old
Detection of Nucleic Acid Sequence Differences Using Coupled Ligase Detection and Polymerase Chain Reactions 6,027,889Robert P. Hammer, Francis Barany, Matthew Lubin, George Barany
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1999

Patent Patent Number Innovators
Use of Ketorolac for Treatment of Squamous Cell Carcinomas of the Oral Cavity or Oropharynx (Gift from Proctor & Gamble)RE. 36419Kotha Subbaramaiah, Paul Francis Cavanaugh Jr., Andrew Dannenberg
D-Methadone, A Nonopioid Analegsic 6,008,258Charles E. Inturrisi
DNA Molecule Encoding for Cellular Uptake of Mycobacterium Tuberculosis and Uses Thereof6,008,201Lee W. Riley
Minimally Invasive Gene Therapy Delivery Device 5,997,509Ronald G. Crystal, Todd K. Rosengart, Ray Hartman
A Method for the Treatment of Conditions Mediated by Collagen Formation together with Cell Proliferation by... 5,965,586Timothy A. McCaffrey, Hartmut Hanauske-Abel, Robert Walter Grady
A Method for the Treatment of Fibroproliferative Disorders by Application of Inhibitors of Protein Hydroxylation 5,965,585Timothy A. McCaffrey, Hartmut Hanauske-Abel, Robert Walter Grady
Regulating Gene Expression Using Retinoids with CH2OH or Related Groups at the Side Chain Terminal Position5,962,534Alexander W. Langston, Charles Achkar, Lorraine J. Gudas, Koji Nakanishi, Fadila Derguini, Jochen Buck
Treating Diseases of the Anterior Horn Cells5,952,357Mindy Lipson Aisen, John P. Blass, Gary Gibson
Method for Treating Patients with Impaired Cognitive or Perceptual Function 5,938,688Nicholas D. Schiff
Method for Performing Magnetic Resonance Angiography Over a Large Field of View Using Table Stepping 5,928,148Yi Wang, Howard M. Lee, Neil M. Khilnani
KSHV Positive Cell Lines5,908,773Leandros Arvanitakis, Enrique Mesri, Ethel Cesarman, Daniel M. Knowles
Blocking Induction of Tetrahydrobiopterin to Block Induction of Nitric Oxide Synthesis 5,880,124Steven S. Gross
Blocking Induction of Tetrahydrobiopterin to Block Induction of Nitric Oxide Synthesis5,877,176Steven S. Gross
Blocking Utilization of Tetrahydrobiopterin to Block Induction of Nitric Oxide Synthesis5,874,433Steven S. Gross
Adenoviral-Mediated Gene Transfer to Adipocytes5,869,037Ronald G. Crystal, Christopher J. MaGovern
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1998

Patent Patent Number Innovators
Transgenic Mouse Deficient in Inducible Nitric Oxide Synthase5,850,004John MacMicking, John S. Mudgett, Carl F. Nathan
Method for Inhibiting Viral Replication in Eukaryotic Cells and of Inducing Apoptosis of Virally-Infected Cells 5,849,587Linda Andrus, Axel Hanauske, Hartmut Hanauske-Abel, Robert Walter Grady, Paul Szabo
Method for the Production of Non-Group C Adenoviral Vectors 5,849,561Erik S. Falck-Pedersen
Gene Transfer Therapy Delivery Device & Method5,846,225Todd K. Rosengart, Charles A. Mack, Ray Hartman
MAGE mAb5,843,448Yao-Tseng Chen, Wolfgang Rettig, Lloyd J. Old, Elisabeth Stockert, Yachi Chen, Pilar Garin-Chesa, Thierry Boon-Falleur, Pierre Van Bruggen
Non-Group C Adenoviral Vectors5,837,511Ronald G. Crystal, Andrea Mastrangeli, Erik S. Falck-Pedersen, D. Karil Abrahamsen
Thermostable Ligase-Mediated DNA Amplification System for the Detection of Genetic Disease5,830,711John A. Zebala, Francis Barany, Deborah Nickerson, Leroy Hood, Robert J. Kaiser
Affinity Purified Heparin5,807,982Timothy A. McCaffrey, D. G. Falcone
Isolated Nucleic Acid Molecule Encoding an Esophageal Cancer Associated Antigen, the Antigen Itself & Use Thereof5,804,381Matthew Scanlan, Yao-Tseng Chen, Ali Gure, Lloyd J. Old
A Method for the Treatment of Fibroproliferative Disorders by Application of Inhibitors ofProtein Hydroxylation 5,789,426Timothy A. McCaffrey, Hartmut Hanauske-Abel, Robert Walter Grady
Regulating Gene Expression Using Retinoids with CH2OH or Related Groups at the Side Chain Terminal Position5,786,391Alexander W. Langston, Charles Achkar, Lorraine J. Gudas, Koji Nakanishi, Fadila Derguini, Jochen Buck
Compositions and Methods to Promote Homologous Recombination in Eukaryotic Cells and Organisms 5,780,296William K. Holloman, Eric B. Kmiec
Treatment and Diagnosis of Prostate Cancer5,773,292Neil H. Bander
Arginine antagonists for inhibition of systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor 5,770,623Steven S. Gross, Roberto Levi, Robert Kilbourn, Owen W. Griffith
Chimeric Adenoviral Fiber Protein and Methods of Using Same5,770,442Thomas J. Wickham, Joseph T. Bruder, Petrus W. Roelvink, Erik S. Falck-Pedersen, Jason Gall, Imre Kovesdi
DNA ENcoding Inducible Nitric Oxide Synthase5,766,909 Qiao-Wen Xie, Richard A. Mumford, Carl F. Nathan, Jimmy R. Calaycay
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1997

Patent Patent Number Innovators
DNA Polymerase III Holoenzyme from Escherichia Coli5,668,004Michael O'Donnell
Use of Ketorolac for Treatment of Squamous Cell Carcinomas of the Oral Cavity or Oropharynx5,626,838Kotha Subbaramaiah, Paul Francis Cavanaugh Jr., Andrew Dannenberg
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1996

Patent Patent Number Innovators
Process for Reconstituting the Polymerase III and other Subassemblies of E. coli DNA Polymerase III Holoenzyme from Peptide Subunits 5,583,026Michael O'Donnell
Blocking Utilization of Tetrahydrobiopterin to Block Induction of Nitric Oxide Synthesis5,502,050Steven S. Gross
Thermostable Ligase-Mediated DNA Amplification System for the Detection of Genetic Disease 5,494,810John A. Zebala, Francis Barany, Deborah Nickerson, Leroy Hood, Robert J. Kaiser
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1995

Patent Patent Number Innovators
Method and Apparatus for the Treatment of Complicated Retinal DetachmentsB1 5,037,384Stanley Chang
Method for treating systemic hypotension caused by sepsis or cytokine using arginase in combination with an .alpha..sub.1 adrenergic agonist 5,395,612Steven S. Gross, Roberto Levi, Owen W. Griffith
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1994

Patent Patent Number Innovators
Method and Apparatus for the Treatment of Complicated Retinal DetachmentsB1 5,037,384Stanley Chang
Ultrasound System for Corneal Biometry 5,331,962Ronald H. Silverman, Donald Jackson Coleman
System for Ultrasonically Determining Corneal Layer Thickness and Shape 5,293,871Donald Jackson Coleman, Dan Z. Reinstein, Lizzi L. Frederic, Ronald H. Silverman
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1993

Patent Patent Number Innovators
Nitric Oxide Synthesis Inhibitors for Potentiating the Action of Pressor Agents in Certain Hypotensive Patients5,216,025Roberto Levi, Robert Kilbourn, Steven S. Gross
Use of Arginase to Control Nitric Oxide Formation5,196,195Owen W. Griffith
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1992

Patent Patent Number Innovators
Diagnosis of Neuronal Disroders & Screening Potential Therapeutic Agents Thereof5,134,062John P. Blass
Purified Inducible Nitric Oxide Synthase Flavoprotein5,132,407Carl F. Nathan, Dennis Stuehr
Antimicrobial Proteins, Compositions Containing Same & Uses Thereof5,087,569Carl F. Nathan, Joelle Gabay
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1991

Patent Patent Number Innovators
Isolating Aminoarginine and Use to Block Nitric Oxide Formation in Body5,059,712Owen W. Griffith
Method of detecting the presence of anomalies in biological tissues and cells in natural and cultured form by infrared spectroscopy 5,038,039Patrick Wong, Basil Rigas
Method & Apparatus for the Treatment of Complicated Retinal Detachments5,037,384Stanley Chang
Method of using arginine derivatives to inhibit systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor 5,028,627Steven S. Gross, Roberto Levi, Robert Kilbourn, Owen W. Griffith