A diet rich in plant foods has been suggested to reduce the risk of cancer, diabetes, heart disease, and many other lifestyle-related diseases. Like all plant foods, apples – especially the peels – contain naturally occurring nutrients that have potent antioxidant and anti-inflammatory activity. AppleBoost is packaged with no chemical alterations, just 100% organic dried apple peel powder

Licensee: Leahy Orchards, Inc.

Messenger boosts yields in field crops and yard plants. Messenger is based on a new proprietary technology called Harp-N-Tek that was discovered at Cornell University. Messenger stimulates a plant’s growth and defense mechanisms to improve the plant’s ability to grow and protect itself from stresses caused by adverse environmental conditions. Messenger is an environmentally friendly product that has been approved by the Environmental Protection Agency for disease management and yield enhancement.

Licensee: Eden Bioscience

MightyPlant is a plant food product that uses Harp-N-Tek protein technology to produce an enhanced fertilizer. MightyPlant starts with the highest quality, water-soluble complete fertilizer components available, including a full compliment of the essential micronutrients plants need for a balanced diet. The fertilizer is produced by one of the leading manufacturers of professional grade, water soluble fertilizers used by commercial greenhouse and nursery growers around the world.

Licensee: Eden Bioscience

OptiPhos releases more phosphorous from feed grain in poultry and swine than any other phytase product. This results in an enhanced diet for the animal as inorganic phosphate is replaced by energy. In addition, OptiPhos benefits the environment as substantially less phosphorus is released onto the land. OptiPhos is available in product forms for pelleted and non-pelleted diets, and even comes in a liquid form. OptiPhos was approved by the United States Food and Drug Administration in July 2005.

Licensee: Phytex LLC

PlantShield™ HC (a wettable powder formulation) protects roots, stems, and leaves from many pathogens. It blocks and actively attacks pathogens by dissolving their cell wall; ensuring uninterrupted plant growth and a healthier root system. PlantShield™ HC is a preventative biofungicide and should be applied to "clean" plants. The active ingredient, Trichoderma harzianum, strain T-22, grows only on the outside of roots, shielding the roots from damaging pathogenic fungi. PlantShield™ HC is compatible with fertilizers, algaecides, insecticides, disinfectants, miticides, herbicides, growth regulators, and nearly all fungicides.

Licensee: BioWorks, Inc.

RootShield™ is a new and improved formulation of PlantShield™ HC - available with a water soluble carrier or in granular form. RootShield™ protects roots from certain fungal pathogenic strains. The active ingredient, Trichoderma harzianum, strain T-22, blocks and actively attacks pathogens by "eating" them; ensuring uninterrupted plant growth. RootShield™ is non-toxic to humans, animals, and is environmentally safe.

Licensee: BioWorks, Inc.

CD36 is a cell surface class B scavenger receptor. CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signaling and adapter molecules. CD36 binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It may function as a cell adhesion molecule. CD36 directly mediates the adherence of erythrocytes harboring the malaria parasite, Plasmodium falciparum, with the lining of small veins of various organs. This may cause microvascular occlusion, which is believed to contribute to the acute pathology of malaria. It also binds long chain fatty acids and may function in their transport and/or as a regulator of fatty acid transport.

Licensees: BD Biosciences - Pharmingen, Cayman Chemical Company, Inc., Hycult biotechnology b.v., Millipore Corporation, Novus Biologicals, LLC, & Santa Cruz Biotechnology, Inc.

The set is composed of 24 different instruments, including hooks, round dissectors, spatula dissectors, elevators, micro-curettes, whirlybird picks, cup forceps, and an Angot-Vanecloo Retractor with malleable blade for brain retraction as well as the MicroFrance™ Bipolar Neuro-otology coagulating forceps, all of which have been designed specifically for lateral skull base surgery. The instruments have slim profiles for superior access, and offer a range of working tips for exceptional control and precision in diffcult to reach areas.

Licensee: Medtronic Xomed Inc.

CoAxia has developed the NeuroFlo™ catheter as a device for augmenting the blood flow to the brain, and in particular to increase blood flow in the collateral blood vessels to augment perfusion in the ischemic penumbra. NeuroFlo™ partially restricts blood flow in the descending aorta, diverting blood flow from the lower extremities to the cerebral collaterals. The NeuroFlo™ catheter itself is a unique, dual-balloon endovascular device. It is inserted through the femoral (leg) artery into the descending aorta and has independently inflatable balloons located immediately above and below the renal (kidney) arteries. The balloons are sequentially inflated to produce occlusions of approximately 70%. The balloons are left inflated for 45 minutes and are then removed and treatment is complete.

Licensee: CoAxia, Inc.

Perfluoron® Liquid sold by Alcon Laboratories enables eye surgeons to operate more easily by acting as a substitute for normal eye fluids. A combination of high vapor pressure, low viscosity, optical clarity, and high specific gravity yields superior control and performance during surgical applications, including LASIK surgery and proliferative viteoretinopathy.

Licensee: Alcon Laboratories

The Champion™ pET SUMO Protein Expression System offers a new and important tool for high-level soluble expression of proteins and peptides with native n-termini. The companion SUMO Protease enzyme works with the great specificity and efficiency on most substrates in a wide range of temperatures without undue damage to the protein of interest. The Champion pET SUMO Protein Expression System uses a small ubiquitin-like modifier (SUMO) to allow expression, purification, and generation of native proteins in E. coli.

Licensee: Invitrogen

The Ras switch operates by alternating between an active, GTP-bound state and an inactive, GDP-bound state. The assay uses the Ras-binding domain (RBD) of the Ras effector kinase Raf1. The Raf-RBD domain has been shown to bind specifically to the GTP-bound form of Ras proteins. The assay provides a simple means of quantitating Ras activation in cells. The amount of activated Ras is determined by a western blot using a Ras specific antibody.

Licensees: Active Motif, Inc., Cytoskeleton, Inc., & Millipore Corporation

This product is a breakthrough in fiber optic cross-connect systems. Now users can dynamically manage and troubleshoot their fiber network from a Network Operations Center, streamlining their fiber operations. At price points 20 times lower than previous optical switches, the FiberConnect costs less than most carriers' present manual fiber management solutions. Functions include remote troubleshooting, network installation verification, fiber protection switching, and hands-free network maintenance. At these prices, and with its carrier-class reliability features, the FiberConnect is at home in FTTx networks, central office environments, network demarcation points, data centers, and customer premises.

Licensee: Calient Networks, Inc.

Multiphoton microscopy (MPM) systems by Carl Zeiss use femto-(10-15) second lasers. This pulsed, ultrafast infrared laser excites fluorescent dyes at the focus only - the only place where photon density is high enough to produce fluorescence. This focus results in only a small amount of their light being absorbed by biological tissues, compared with visible excitation light. The result is deep tissue penetration of the excitation light, with low absorption and next to no scattering loss and only minimal phototoxic effects.

MPM offers a decisive advantage in the long-term observation of biological processes: the device’s point excitation allows for a significant reduction in phototoxicity, as the light has an impairing effect only in the focus. Whether it is intravital imaging, long-term observation of developmental processes, or high-resolution 3D imaging, MPM delivers true-to-detail and high-contrast images and allows scientists to generate images of surface to very deep-lying tissue with subcellular resolution in a gentle way.

Licensee: Carl Zeiss MicroImaging GmbH

MicroMounts™ are the highest performance tools for manipulating and mounting protein crystals, virus crystals, and small molecule/inorganic crystals, as well as, a wide range of other small, fragile samples. They are ideal for both conventional and high-throughput X-ray crystallography applications

MicroMesh™ Mounts are the tool of choice for microcrystal crystallography and diffraction experiments, especially at microfocus beamlines. They have been used in de novo protein structure determination from crystals as small as 5 um. They are excellent for rod shaped crystals, and in particular are superior to mounts with elliptical apertures, because the mesh provides continuous, gentle support for rods of all sizes. MicroMeshes produce the smallest background scatter of any commercial mount. Their sieve-like action allows easy retrieval of sub-30 um crystals.

Licensee: Mitegen

These tools are designed for use with samples from a fewmicrometers to a millimeter in size. Unlike other microtools, Mitegen's patent-pending MicroTools™ have tips made from soft, flexible microfabricated polymer films. The curvature of the tips gives them rigidity, but they can still easily be flexed to, e.g., slide flat along the well bottom in a multiwell plate, simplifying sample retrieval. These tools are far less likely to damage fragile samples than metal microtools, and are optically and X-ray transparent. They are well suited for use with protein crystals, single cells and other small samples.

Licensee: Mitegen

The Speedster™ family of Field Programmable Gate Arrays (FPGAs) from Achronix Semiconductor are the world’s fastest programmable logic devices. Speedster™ FPGAs are fully reprogrammable, yet still capable of operating at up to 1.5 GHz system performance, which represents a three-fold increase in performance over existing FPGAs. The Speedster™ FPGA family is suitable for a wide range of telecommunications, networking, video, digital signal processing, high-performance computing, imaging, industrial and military applications.

Licensee: Achronic Semiconductor Corporation

Geneva® 11 is a 1978 cross of 'M-26 X Robusta 5' crabapple. Geneva® 11 shows very good precocity with higher yield efficiency than many commercial rootstocks. It is moderately resistant to fire blight, infections are very rare. With high fruit effciency and large fruit size, this rootstock works well in many commercial orchards, and also does well in replant sites.

Licensee: Trceo, Inc.

Geneva® 16 is a 1981 cross of 'Ottawa 3 X Malus floribunda'. Geneva® 16 is hypersensitive to at least one common latent virus. It is tolerant to collar rot, nearly immune to fire blight, and immune to scab (black spot). In the orchard, Geneva® 16 is non-brittle and well-anchored.

Licensee: Treco, Inc.

Geneva® 30 originated from a cross of 'Robusta 5 X M-9'. Geneva® 30 show to be very winter hardy with extremely high yield efficiency. Geneva® 30 is resistant to fire blight (Erwinia amylovora) and has a high tolerance for crown rot. Burr knots are rare and it is more broadly adaptable to soil conditions.

Licensee: Treco, Inc.

The OptiGen prcd test is done on a small sample of blood from the dog. The test analyzes the specific DNA mutation causing the prcd-PRA. The OptiGen test detects the mutant, abnormal gene copy and the normal gene copy. The result of the test is a genotype and allows separation of dogs into three groups: Normal/Clear (homozygous normal), Carrier (heterozygous), and Affected (homozygous mutant).

Licensee: Optigen, LLC

The OptiGen genetic test for CEA/CH provides a powerful management tool for the breeder. This genetic test can distinguish all three genetic states – normal, carrier and affected. With this information, the breeder can plan matings that avoid producing any affected dogs by always selecting one parent that is normal. The other parent can be normal, carrier or even affected, and no affected dogs will result. This breeding recommendation is a big step forward, especially for breeds and countries where frequency of CEA/CH is much lower. Earlier advice cautioned against breeding affected dogs, their parents, their ospring or their siblings (unless eye exams before 3 months of age demonstrate the sibling is unaffected).

Licensee: Optigen, LLC

The CSNB test is a DNA-based test that provides, for the first time, a method to unequivocally identify Congenital Stationary Night Blindness, or CSNB, in the Briard. This will control the gene frequency in the breed so as to prevent producing puppies affected with the disease. Reliable identification of dogs that do not carry disease genes is the key to controlling autosomal recessive diseases. The OptiGen CSNB test enables 100% accurate identification of these dogs.

Licensee: Optigen, LLC

The IDEXX HerdChek™ BVD Antigen Test Kit is the only USDA-licensed test for detecting persistently infected (PI) calves. The kit offers superior sensitivity, speed, and simplicity compared to other test methods. The HerdChek™ BVD Antigen Test Kit tests calves less than six months of age, comes with easy to use, highly stable reagents resistant to temperature fluctuations, and offers simple ear-notch sampling with results in as little as five hours.

Licensee: IDEXX Laboratories, Inc.

Pinnacle I.N. is the first intranasal equine strangles vaccine available to U.S. horse owners. Its exclusive delivery system eliminates intramuscular inflammation and lameness that may be associated with vaccines administered parenterally. Dosing is easy with Pinnacle I.N. A 2 mL dose is placed in one nostril, followed by a second dose two to three weeks later. Pinnacle I.N. stimulates mucosal immunity at the site of the natural infection for a fast, effective response.

Licensee: Wyeth

ReproCHEK™...a worldwide exclusive

The first canine pregnancy test based on detection of relaxin

Allows for early detection of pregnancy

Use to diagnose pseudocyesis and embryonal resorption

ReproCHEK™ can monitor pregnancy throughout gestation

Licensee: Synbiotics Corporation